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[急性白血病中原始细胞鉴别的功能标准]

[Functional criteria for differentiating blast cells in acute leukemia].

作者信息

Nedialkova M, Dobreva A, Bakalova S, Georgieva B

出版信息

Vutr Boles. 1983;22(4):63-6.

PMID:6675286
Abstract

Eighty nine patients were examined that had various clinical-morphological forms of acute leukosis, the phagocytic activity of leukosis cells being determined and the synthesis and secretion of lysozyme by them followed up, reflected in its serum level. Leukosis cells of monoblast type were established to have the ability to ingest staphylococci, candida and particles of latex, as well as to synthesize lysozyme, confirmed by the highly elevated enzyme quantity in the sera of the patients. Those functional manifestations are proposed to be used as additional criteria in the determination of cellular type of leukosis proliferation.

摘要

对89例患有各种临床形态学类型急性白血病的患者进行了检查,测定白血病细胞的吞噬活性,并追踪其溶菌酶的合成与分泌情况,血清水平可反映这一情况。已确定单核母细胞型白血病细胞有吞噬葡萄球菌、念珠菌和乳胶颗粒的能力,也能合成溶菌酶,这一点在患者血清中酶含量大幅升高得到证实。建议将这些功能表现作为确定白血病增殖细胞类型的附加标准。

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