幼年和青年大鼠自然发生的致死性细小病毒感染
Naturally occurring lethal parvovirus infection of juvenile and young-adult rats.
作者信息
Coleman G L, Jacoby R O, Bhatt P N, Smith A L, Jonas A M
出版信息
Vet Pathol. 1983 Jan;20(1):49-56. doi: 10.1177/030098588302000105.
PMID:6681574
Abstract
A lethal disease characterized by hemorrhage and necrosis of the brain, testes, and epididymides developed in young adult rats housed in specific pathogen free quarters. Morphological, virological, and serological investigations of the outbreak indicated that the probable causative agent was rat virus (Kilham), a common parvovirus of rats that usually induces persistent, asymptomatic infection in adult rats.
摘要
在饲养于无特定病原体环境中的成年幼鼠身上，出现了一种以脑、睾丸和附睾出血及坏死为特征的致命疾病。对此次疫情进行的形态学、病毒学和血清学调查表明，可能的致病因子是大鼠病毒（基尔汉姆病毒），这是一种常见的大鼠细小病毒，通常在成年大鼠中引发持续性无症状感染。
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