Starkova N T, Zhienkulova A K
Probl Endokrinol (Mosk). 1983 Jan-Feb;29(1):39-42.
The results of investigation and treatment of 8 patients with initial hypothyrosis, galactorrhea and disturbed menstrual function are presented. The initial hypothyrosis in patients with galactorrhea may have a latent form and/or be combined with intracellular hypophyseal tumor. Sometimes the first sign of the syndrome mentioned is abnormal lactation. The prolactin level is elevated in these patients and its depot increased. In latent hypothyrosis the thyrotropin content is within normal, its response to thyroliberin stimulation being enhanced and prolonged. Thyroid hormone therapy is effective in these patients. It was concluded that thyroid hormone substituting therapy is an adequate method for the treatment of initial hypothyrosis, galactorrhea and disordered menstrual function.
本文介绍了8例初发性甲状腺功能减退症伴溢乳及月经功能紊乱患者的调查和治疗结果。溢乳患者的初发性甲状腺功能减退症可能呈潜伏形式和/或合并垂体细胞内肿瘤。有时上述综合征的首发症状是异常泌乳。这些患者的催乳素水平升高，其储存量增加。在潜伏性甲状腺功能减退症中，促甲状腺激素含量正常，其对促甲状腺素释放激素刺激的反应增强且延长。甲状腺激素疗法对这些患者有效。得出的结论是，甲状腺激素替代疗法是治疗初发性甲状腺功能减退症、溢乳及月经功能紊乱的一种适当方法。
