顶头孢霉β-内酰胺阴性突变体中三肽δ-（L-α-氨基己二酰基）-L-半胱氨酰-D-缬氨酸生物合成的研究
A study of the biosynthesis of the tripeptide delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine in a beta-lactam-negative mutant of Cephalosporium acremonium.
作者信息
Adlington R M, Baldwin J E, Lopez-Nieto M, Murphy J A, Patel N
出版信息
Biochem J. 1983 Sep 1;213(3):573-6. doi: 10.1042/bj2130573.
Abstract
A cell-free extract of Cephalosporium acremonium (Takeda N-2) was obtained that synthesized the tripeptide delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine and also the dipeptide delta-(L-alpha-aminoadipyl)-L-cysteine from the corresponding L-amino acids.
摘要
获得了顶头孢霉（武田N-2）的无细胞提取物，该提取物能从相应的L-氨基酸合成三肽δ-（L-α-氨基己二酰基）-L-半胱氨酰-D-缬氨酸以及二肽δ-（L-α-氨基己二酰基）-L-半胱氨酸。
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A study of the biosynthesis of the tripeptide delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine in a beta-lactam-negative mutant of Cephalosporium acremonium.顶头孢霉β-内酰胺阴性突变体中三肽δ-（L-α-氨基己二酰基）-L-半胱氨酰-D-缬氨酸生物合成的研究
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Antimicrob Agents Chemother. 1987 Feb;31(2):357-9. doi: 10.1128/AAC.31.2.357.
本文引用的文献
1
Delta-(alpha-aminoadipyl)cysteinylvaline synthetase.δ-（α-氨基己二酰）半胱氨酰缬氨酸合成酶
Methods Enzymol. 1975;43:471-3. doi: 10.1016/0076-6879(75)43105-6.
2
Cell-free conversion of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine into an antibiotic with the properties of isopenicillin N in Cephalosporium acremonium.顶头孢霉中无细胞体系将δ-（L-α-氨基己二酰基）-L-半胱氨酰-D-缬氨酸转化为具有异青霉素N特性的抗生素。
Biochem J. 1979 Nov 15;184(2):427-30. doi: 10.1042/bj1840427.
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