Milligan S R, Mirembe F M
J Reprod Fertil. 1984 Jan;70(1):1-6. doi: 10.1530/jrf.0.0700001.
Uterine vascular permeability and tissue blood volume during the development of the oil-induced decidual cell reaction (DCR) in ovariectomized steroid-treated rats were assessed by measuring the extravascular accumulation of 125I-labelled human serum albumin and the tissue content of 51Cr-labelled red cells 30 min after intravenous administration. Within 15 min of oil instillation into one uterine horn, the vascular permeability of the horn was significantly elevated. Permeability rose to a sharp peak (10 times control levels) 9 h after oil instillation, but dropped to 5 times control values by 12 h and continued a steady decline over the next 7 days. Although a marked increase in uterine weight was associated with the development of the DCR, there was no significant change in blood volume/g tissue until 4 days after oil instillation.
通过静脉注射后30分钟测量125I标记的人血清白蛋白的血管外蓄积量以及51Cr标记的红细胞的组织含量，评估卵巢切除并经类固醇处理的大鼠在油诱导蜕膜细胞反应（DCR）发展过程中的子宫血管通透性和组织血容量。在向一个子宫角注入油后的15分钟内，该子宫角的血管通透性显著升高。注入油后9小时，通透性急剧上升至峰值（为对照水平的10倍），但到12小时时降至对照值的5倍，并在接下来的7天内持续稳定下降。尽管子宫重量的显著增加与DCR的发展相关，但直到注入油后4天，每克组织的血容量才出现显著变化。
