Westenskow D R, Cutler C A, Wallace W D
Crit Care Med. 1984 Mar;12(3):183-7. doi: 10.1097/00003246-198403000-00006.
In the critically ill patient the monitoring of oxygen consumption (VO2) and carbon dioxide production (VCO2) can identify abnormalities in tissue perfusion and metabolism. A patient's metabolic utilization can be calculated by indirect calorimetry, once VO2 and VCO2 are measured. This paper evaluates a compact instrument designed for monitoring VO2 and VCO2 in the critically ill adult. Accuracy was measured under controlled laboratory conditions using oxygen-enriched air, PEEP, and intermittent mandatory ventilation (IMV). Accuracy averaged 1.3% for VO2 and 0.9% for VCO2 when room air was used. Accuracy was 11.7% for VO2 and 6.8% for VCO2 when 80% oxygen was used. PEEP of 30 cm H2O had little effect on accuracy. IMV at 2 breath/min (room air) resulted in an accuracy of 4.0% and 4.1% for VO2 and VCO2, respectively.
在危重症患者中,监测氧耗量(VO2)和二氧化碳产生量(VCO2)可识别组织灌注和代谢异常。一旦测量出VO2和VCO2,就可以通过间接测热法计算患者的代谢利用率。本文评估了一种专为监测危重症成年患者的VO2和VCO2而设计的紧凑型仪器。在使用富氧空气、呼气末正压通气(PEEP)和间歇指令通气(IMV)的受控实验室条件下测量了准确性。使用室内空气时,VO2的平均准确性为1.3%,VCO2为0.9%。使用80%氧气时,VO2的准确性为11.7%,VCO2为6.8%。30 cm H2O的PEEP对准确性影响不大。2次呼吸/分钟(室内空气)的IMV导致VO2和VCO2的准确性分别为4.0%和4.1%。