Whited R E
Laryngoscope. 1984 Mar;94(3):367-77. doi: 10.1288/00005537-198403000-00014.
A series of 200 patients having endotracheal intubation between 2 and 24 days were studied prospectively. The data was organized into 3 groups as follows: Group I: 2 to 5 days intubation, (50); Group II: 6 to 10 days intubation, (100); and Group III: 11 to 24 days intubation, (50). For the Group I population, the most significant injury is in the posterior commissure of the larynx which in this site leads to acute and chronic sequelae. At these intubation times, cuff site injury has not been prominent. Despite the selection of patients for conversion to tracheotomy in order to prevent complications, there is an increased incidence of significant sequelae in Group II population. A most noticeable trend accompanying the increased incidence is the changing nature of the resultant stenosis to include continuous damage from the posterior glottis through the cervical trachea. These trends become evident in those patients having intubation times greater that 7 days. In Group III population, the increased incidence, as well as the severity of post-intubation complications become clearly evident. Conversion to tracheotomy before serious organ disruption occurs at these prolonged intubation times is preventative.
对200例在2至24天内行气管插管的患者进行了前瞻性研究。数据被分为以下3组：第一组：插管2至5天（50例）；第二组：插管6至10天（100例）；第三组：插管11至24天（50例）。对于第一组患者，最显著的损伤发生在喉后联合处，该部位会导致急慢性后遗症。在这些插管时间段，套囊部位损伤并不突出。尽管为预防并发症选择了患者进行气管切开术，但第二组患者中严重后遗症的发生率仍有所增加。随着发生率增加，一个最明显的趋势是所导致狭窄的性质发生变化，包括从声门后直至颈段气管的持续性损伤。这些趋势在插管时间超过7天的患者中变得明显。在第三组患者中，插管后并发症的发生率增加以及严重程度都变得明显。在这些延长的插管时间导致严重器官损害之前进行气管切开术具有预防作用。
