淋巴细胞对流感病毒血凝素和神经氨酸酶亚基的反应。
Lymphocyte responses to hemagglutinin and neuraminidase subunits of influenza virus.
作者信息
Ruben F, Bachmayer H
出版信息
J Clin Microbiol. 1978 Jun;7(6):558-61. doi: 10.1128/jcm.7.6.558-561.1978.
Abstract
The responses of peripheral lymphocytes to purified hemagglutinin and neuraminidase subunits and other components of an influenza. A virus were measured in 21 normal adults and compared with antibody titers. All had influenza antibodies and demonstrated influenza antigen recognition by lympho-proliferative responses. There was a significantly greater response to the two purified influenza virus surface antigens, hemagglutinin and neuraminidase, than to either whole intact virus or its separated subviral core. No correlation between magnitudes of antibody titers and lymphocyte responsiveness was observed.
摘要
在21名正常成年人中检测了外周淋巴细胞对纯化的血凝素和神经氨酸酶亚基以及甲型流感病毒其他成分的反应，并与抗体滴度进行了比较。所有人都有流感抗体，并通过淋巴细胞增殖反应表现出流感抗原识别能力。与完整的病毒或其分离的病毒亚核心相比，对两种纯化的流感病毒表面抗原血凝素和神经氨酸酶的反应明显更强。未观察到抗体滴度大小与淋巴细胞反应性之间的相关性。
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