Lairscey R G, Kelly M T
J Clin Microbiol. 1984 Mar;19(3):318-20. doi: 10.1128/jcm.19.3.318-320.1984.
This study presents an evaluation of a commercial system for the MIC testing of single drugs dehydrated in disposable plastic trays (Precept, Austin Biological Laboratories, Inc., Austin, Tex.). The commercial system was compared with a reference agar dilution method, and 203 clinical bacterial isolates were tested by each method. For a total of 767 determinations, there was 94.2% agreement between the two methods, and of the discrepancies encountered, 0.8% were very major, 2.1% were major, and 2.9% were minor. The results suggest that the Precept system may provide a practical and reliable method for MIC determinations of individual antimicrobial agents.
本研究对一种用于在一次性塑料托盘中脱水的单一药物进行最低抑菌浓度(MIC)测试的商业系统(Precept,奥斯汀生物实验室公司,德克萨斯州奥斯汀)进行了评估。将该商业系统与参考琼脂稀释法进行比较,每种方法对203株临床细菌分离株进行了测试。在总共767次测定中,两种方法之间的一致性为94.2%,在遇到的差异中,0.8%为极重大差异,2.1%为重大差异,2.9%为微小差异。结果表明,Precept系统可能为个体抗菌药物的MIC测定提供一种实用且可靠的方法。