给予大鼠的1,5-脱水葡萄糖醇的消除情况。
The elimination of 1,5-anhydroglucitol administered to rats.
作者信息
Pitkänen E, Pitkänen O
出版信息
Experientia. 1984 May 15;40(5):463-5. doi: 10.1007/BF01952387.
PMID:6723908
Abstract
Rat serum contains natural 1,5-anhydroglucitol. Injected or orally administered 1,5-anhydroglucitol was efficiently reabsorbed by the renal tubuli via a mechanism which had a saturation point at high serum 1,5- anhydroglucitol levels. The compound had a slow turnover rate in the body; its half-life is approximately 3 days. The compound was readily absorbed in the gut when administered orally.
摘要
大鼠血清中含有天然1,5-脱水葡萄糖醇。注射或口服的1,5-脱水葡萄糖醇可通过一种在高血清1,5-脱水葡萄糖醇水平时具有饱和点的机制被肾小管有效重吸收。该化合物在体内的周转速度较慢；其半衰期约为3天。口服给药时，该化合物很容易在肠道被吸收。
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