Ponvert C, Galoppin L, Burtin C, Paupe J, Canu P
Pharmacology. 1984;28(4):235-40. doi: 10.1159/000137968.
Hairless rats receiving a deprived Mg2+ diet developed long-lasting inflammatory dermatosis which was not influenced by treatments with mepyramine, cimetidine, aspirin or indomethacin. Dermatosis did not appear in deprived rats treated with intraperitoneal injections of Mg2+, or with dexamethasone. Histamine and prostaglandins did not seem to be involved in this dermatosis. The possible role of leucotrienes is discussed.
接受低镁饮食的无毛大鼠会患上持续时间较长的炎性皮肤病，这种皮肤病不受美吡拉敏、西咪替丁、阿司匹林或吲哚美辛治疗的影响。在用腹腔注射镁离子或地塞米松治疗的低镁大鼠中未出现皮肤病。组胺和前列腺素似乎与这种皮肤病无关。文中讨论了白三烯可能发挥的作用。
