Rotteveel J J, Renier W O, Weemaes C M, De Witte T J
Tijdschr Kindergeneeskd. 1984 Apr;52(2):59-63.
Subacute sclerosing panencephalitis is a rare slowly progressive neurodegenerative disease in children and young adults. The course of the disease is 'typically' progressive until a vegetative state and death. Otherwise, the course might be 'atypical', with periods of relative stability or even some improvement. We describe two patients one of whom showed the typical course of the disease, whereas the other one showed the atypical form. Both patients were treated with plasmapheresis without noticeable favorable effects. The clinical symptomatology, the pathogenesis and the various therapeutical approaches are discussed.
亚急性硬化性全脑炎是一种罕见的、在儿童和青年中缓慢进展的神经退行性疾病。该疾病的病程“通常”呈进行性发展，直至进入植物状态并死亡。否则，病程可能是“非典型的”，存在相对稳定期甚至有所改善。我们描述了两名患者，其中一名表现出典型的病程，而另一名则表现为非典型形式。两名患者均接受了血浆置换治疗，但未观察到明显的有益效果。本文讨论了临床症状、发病机制及各种治疗方法。
