Demir R, Erbengi T
Acta Anat (Basel). 1984;119(1):18-26. doi: 10.1159/000145857.
The cytological structure of the Hofbauer cells was investigated in human placentas of the first and second trimesters of gestation. These cells are found in the stromal channel system of the chorionic villi core. Their walls, which are supported by collagen fiber bundles, are produced by reticulum cells and fibroblasts. The cytoplasmic processes of the Hofbauer cells are in contact with the walls of the channels without being associated with them by desmosomal complexes. Some of these cells have features in common with macrophages, such as cytoplasmic processes, larger vacuoles, many pinocytotic vesicles and intracytoplasmic granules. This system of vacuoles and vesicles enables micropinocytotic activity and phagocytosis. This type of Hofbauer cell resembles the typical macrophages. These cells may play a role in the regulation of stromal water content, transportation of ions and the flow of interstitial fluid. The most original finding of this study are long tubes observed in some Hofbauer cells and extending between the nucleus and the extracellular ground substance through the cytoplasm. One of these tubular formations resembles a cilium in structure with three limiting membranes and is filled with a slightly electron-dense substance. This type of Hofbauer cell may transport information between the nucleus and the extracellular ground substance by means of these tubular structures.
在妊娠头三个月和第二个三个月的人胎盘中，对霍夫鲍尔细胞的细胞学结构进行了研究。这些细胞存在于绒毛膜绒毛核心的基质通道系统中。它们的壁由胶原纤维束支撑，由网状细胞和成纤维细胞产生。霍夫鲍尔细胞的细胞质突起与通道壁接触，但不通过桥粒复合体与之相连。其中一些细胞具有与巨噬细胞相同的特征，如细胞质突起、较大的液泡、许多胞饮小泡和胞质颗粒。这种液泡和小泡系统能够进行微胞饮活动和吞噬作用。这种类型的霍夫鲍尔细胞类似于典型的巨噬细胞。这些细胞可能在基质含水量的调节、离子运输和组织液流动中发挥作用。这项研究最原始的发现是在一些霍夫鲍尔细胞中观察到的长管，它们通过细胞质在细胞核和细胞外基质之间延伸。其中一种管状结构在结构上类似于纤毛，有三层限制膜，内部充满了轻度电子致密物质。这种类型的霍夫鲍尔细胞可能通过这些管状结构在细胞核和细胞外基质之间传递信息。
