Bafundo K W, Baker D H, Fitzgerald P R
J Nutr. 1984 Jul;114(7):1306-12. doi: 10.1093/jn/114.7.1306.
Two 14-day growth trials were performed to assess the effects of Eimeria acervulina infection (duodenal coccidiosis) on the Fe-Zn interrelationship in growing chicks. In the first assay, two levels of Fe (0 and 2000 mg/kg) were added to diets that contained either 0 or 52 mg supplemental Zn (from ZnCO3) per kilogram to establish whether excess Fe would affect Zn status of healthy and coccidial-infected chicks. In the second trial, either 0 or 2000 mg Zn/kg was added to diets containing 0 or 500 mg Fe/kg to determine whether Zn could modify Fe utilization. Based on chick performance as well as plasma Zn concentration, excess dietary Fe did not antagonize Zn in either healthy or E. acervulina-infected chicks. Coccidial infection, however, increased liver Fe and decreased intestinal Fe and hemoglobin concentration. Excess dietary Zn reduced performance and Fe content of tissues in both healthy and infected chicks. Coccidial infection ameliorated the adverse effects of excess Zn on performance and tissue Zn concentration and consequently enhanced Fe status of birds fed 2000 mg Zn/kg. These data suggest that the Fe-Zn interaction is a one-directional phenomenon in the chick, i.e., excess Zn reduces Fe utilization but excess Fe does not antagonize Zn.
进行了两项为期14天的生长试验，以评估堆型艾美耳球虫感染（十二指肠球虫病）对生长鸡铁锌相互关系的影响。在第一次试验中，向每千克分别含有0或52毫克补充锌（来自碳酸锌）的日粮中添加两个水平的铁（0和2000毫克/千克），以确定过量的铁是否会影响健康和球虫感染鸡的锌状态。在第二次试验中，向每千克含有0或500毫克铁的日粮中添加0或2000毫克锌/千克，以确定锌是否会改变铁的利用率。基于雏鸡的生产性能以及血浆锌浓度，过量的日粮铁在健康或感染堆型艾美耳球虫的雏鸡中均未拮抗锌。然而，球虫感染增加了肝脏铁含量，降低了肠道铁含量和血红蛋白浓度。过量的日粮锌降低了健康和感染雏鸡的生产性能和组织铁含量。球虫感染减轻了过量锌对生产性能和组织锌浓度的不利影响，从而提高了饲喂2000毫克锌/千克日粮的鸡的铁状态。这些数据表明，在雏鸡中铁锌相互作用是一种单向现象，即过量的锌会降低铁的利用率，但过量的铁不会拮抗锌。
