McCann I L, Holmes D S
J Pers Soc Psychol. 1984 May;46(5):1142-7. doi: 10.1037//0022-3514.46.5.1142.
Forty-three depressed women were randomly assigned to either (a) an aerobic exercise treatment condition in which they participated in strenuous exercise, (b) a placebo treatment condition in which they practiced relaxation exercises, or (c) a no-treatment condition. Aerobic capacity was assessed before and after the 10-week treatment period. Self-reported depression was assessed before, during, and after the treatment period. The results indicated that subjects in the aerobic exercise condition evidenced reliably greater improvements in aerobic capacity than did the subjects in either of the other conditions (p less than .002 in both cases) and that the subjects in the aerobic exercise condition evidenced reliably greater decreases in depression than did subjects in the placebo condition (p = .05) or subjects in the no-treatment condition (p = .001). These results provide the first controlled evidence concerning the effects of strenuous exercise on depression.
43名抑郁症女性被随机分配到以下三种情况之一：(a) 有氧运动治疗组，她们参与剧烈运动；(b) 安慰剂治疗组，她们进行放松练习；(c) 无治疗组。在为期10周的治疗期前后评估有氧运动能力。在治疗期之前、期间和之后评估自我报告的抑郁情况。结果表明，有氧运动组的受试者在有氧运动能力方面的改善明显大于其他两种情况的受试者（两种情况的p值均小于0.002），并且有氧运动组的受试者在抑郁程度上的下降明显大于安慰剂组的受试者（p = 0.05）或无治疗组的受试者（p = 0.001）。这些结果提供了关于剧烈运动对抑郁症影响的首个对照证据。
