Hunkapiller M, Kent S, Caruthers M, Dreyer W, Firca J, Giffin C, Horvath S, Hunkapiller T, Tempst P, Hood L
Nature. 1984;310(5973):105-11. doi: 10.1038/310105a0.
A series of automated instruments that use state-of-the-art chemical methods has been developed for high-sensitivity protein sequencing, DNA synthesis and peptide synthesis. These instruments have been integrated into a centralized microchemical facility in order to promote their use for the study of a variety of biologically interesting problems. This facility has as one of its major functions the development of new chemistries and instrumentation for the structural analysis and synthesis of genes and proteins.
已经开发出一系列使用最先进化学方法的自动化仪器,用于高灵敏度蛋白质测序、DNA合成和肽合成。这些仪器已被整合到一个集中的微化学设施中,以促进其用于研究各种生物学上有趣的问题。该设施的主要功能之一是开发用于基因和蛋白质结构分析与合成的新化学方法和仪器。