Rose J E
Addict Behav. 1984;9(2):189-93. doi: 10.1016/0306-4603(84)90056-x.
Cigarette smokers were presented with puffs from either high (2.5 mg), medium (1.5 mg) or low (.5 mg) nicotine cigarettes in order to determine their ability to discriminate nicotine delivery in tobacco smoke. Puffs were presented in random order during each of two conditions and tar content was controlled by using research cigarettes and a smoke mixing device that varied only nicotine. The first condition allowed olfactory stimuli to be used in discrimination, while the second condition blocked olfaction by occluding subjects' nostrils. In both conditions, subjects discriminated between the nicotine content of different puffs, with higher nicotine puffs rated as significantly stronger (by roughly 50%). Subjective desirability ratings did not vary with nicotine delivery. The implications of the magnitude of change in subjects' ratings for theories of nicotine titration are discussed.
为了确定吸烟者辨别烟草烟雾中尼古丁输送量的能力，研究人员向吸烟者提供了来自高尼古丁（2.5毫克）、中尼古丁（1.5毫克）或低尼古丁（0.5毫克）香烟的烟雾。在两种条件下，烟雾均以随机顺序呈现，且通过使用研究用香烟和仅改变尼古丁含量的烟雾混合装置来控制焦油含量。第一种条件允许嗅觉刺激用于辨别，而第二种条件则通过堵塞受试者鼻孔来阻断嗅觉。在这两种条件下，受试者都能辨别不同烟雾的尼古丁含量，尼古丁含量较高的烟雾被评为明显更强（约强50%）。主观偏好评分并未随尼古丁输送量而变化。本文讨论了受试者评分变化幅度对尼古丁滴定理论的影响。
