Gibb K A, Yee A S, Johnston C C, Martin S D, Nowak R M
Ann Emerg Med. 1984 Jul;13(7):516-20. doi: 10.1016/s0196-0644(84)80517-x.
We evaluated the accuracy of a hand-held breath alcohol analyzer in the rapid determination of blood alcohol levels in the emergency patient with suspected ethanol intoxication. The Alco -Sensor III breath alcohol analyzer was used to measure alcohol levels in orally and nasally obtained end-expiratory breath samples in 55 patients. These levels were compared to directly measured blood alcohol levels. The patients were categorized into cooperative and uncooperative groups. The mean oral breath alcohol level obtained was 0.187 +/- 0.100 g/dL (range, 0.000 to 0.419) while the mean serum level was 0.217 +/- 0.113 g/dL (range, 0.00 to 400). The overall correlation between these two methods of measuring blood alcohol level was strong (r = .879, P less than .001). In cooperative patients the correlation was even stronger (r = .963, P less than .001), while in uncooperative patients the correlation was less but still significant (r = .723, P = .001). Nasally obtained samples correlated well with blood levels in cooperative patients (r = .874, P less than .001), but the correlation was less strong in uncooperative persons (r = .694, P = .003). Our study indicates that the Alco -Sensor III breath alcohol analyzer is sufficiently accurate to be of use in rapidly assessing blood alcohol levels, even when a patient is unable to cooperate fully.
我们评估了一款手持式呼气酒精分析仪在快速测定疑似乙醇中毒急诊患者血液酒精水平方面的准确性。使用Alco -Sensor III呼气酒精分析仪测量了55例患者经口和经鼻采集的呼气末呼吸样本中的酒精水平。将这些水平与直接测量的血液酒精水平进行比较。患者被分为合作组和不合作组。获得的平均经口呼气酒精水平为0.187±0.100 g/dL（范围为0.000至0.419），而平均血清水平为0.217±0.113 g/dL（范围为0.00至400）。这两种测量血液酒精水平方法之间的总体相关性很强（r = 0.879，P < 0.001）。在合作患者中相关性更强（r = 0.963，P < 0.001），而在不合作患者中相关性较弱但仍具有统计学意义（r = 0.723，P = 0.001）。经鼻采集的样本在合作患者中与血液水平相关性良好（r = 0.874，P < 0.001），但在不合作患者中相关性较弱（r = 0.694，P = 0.003）。我们的研究表明，即使患者无法充分配合，Alco -Sensor III呼气酒精分析仪在快速评估血液酒精水平方面也足够准确，可以使用。
