从肾皮质组织中提取氨基糖苷类药物的改进方法。
Improved procedure for extracting aminoglycosides from renal cortical tissue.
作者信息
Giuliano R A, Verpooten G A, Pollet D E, Verbist L, Scharpé S L, De Broe M E
出版信息
Antimicrob Agents Chemother. 1984 Jun;25(6):783-4. doi: 10.1128/AAC.25.6.783.
Abstract
An efficient and reproducible procedure was developed for extracting aminoglycosides from renal cortical tissue. It involves a double homogenization and two rinsings with trichloroacetic acid. A higher recovery is obtained compared with that of other previously reported methods.
摘要
开发了一种从肾皮质组织中提取氨基糖苷类药物的高效且可重复的方法。该方法包括双重匀浆和用三氯乙酸进行两次冲洗。与其他先前报道的方法相比，回收率更高。
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本文引用的文献
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Influence of dose regimen on renal accumulation of aminoglycosides.给药方案对氨基糖苷类药物肾脏蓄积的影响。
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Binding of antibiotics to tissue homogenates.抗生素与组织匀浆的结合
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Distribution of gentamicin and amikacin in rabbit tissues.庆大霉素和阿米卡星在兔组织中的分布。
Antimicrob Agents Chemother. 1977 Jun;11(6):974-7. doi: 10.1128/AAC.11.6.974.
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Stability of dilute solutions of gentamicin and tobramycin.庆大霉素和妥布霉素稀释溶液的稳定性。
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Comparative nephrotoxicity of aminoglycoside antibiotics in rats.氨基糖苷类抗生素对大鼠的比较肾毒性
J Infect Dis. 1978 Oct;138(4):541-5. doi: 10.1093/infdis/138.4.541.
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Nephrotoxicity of gentamicin and tobramycin given once daily or continuously in dogs.庆大霉素和妥布霉素每日一次或持续给药对犬的肾毒性
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Gentamicin disposition and tissue accumulation on multiple dosing.
J Pharmacokinet Biopharm. 1977 Dec;5(6):559-77. doi: 10.1007/BF01059684.
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Comparative nephrotoxicities of gentamicin, netilmicin and tobramycin in the rat.庆大霉素、奈替米星和妥布霉素对大鼠的肾毒性比较
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