光胆红素II
Photobilirubin II.
作者信息
Bonnett R, Buckley D G, Hamzetash D, Hawkes G E, Ioannou S, Stoll M S
出版信息
Biochem J. 1984 May 1;219(3):1053-6. doi: 10.1042/bj2191053.
Abstract
An improved preparation of photobilirubin II in ammoniacal methanol is described. Evidence is presented which distinguishes between the two structures proposed earlier for photobilirubin II in favour of the cycloheptadienyl structure. Nuclear-Overhauser-enhancement measurements with bilirubin IX alpha and photobilirubin II in dimethyl sulphoxide are complicated by the occurrence of negative and zero effects. The partition coefficient of photobilirubin II between chloroform and phosphate buffer (pH 7.4) is 0.67.
摘要
本文描述了一种在氨性甲醇中制备光胆红素II的改进方法。文中给出的证据区分了先前提出的光胆红素II的两种结构，支持环庚二烯基结构。在二甲亚砜中对胆红素IXα和光胆红素II进行核Overhauser增强测量时，由于出现负效应和零效应而变得复杂。光胆红素II在氯仿和磷酸盐缓冲液（pH 7.4）之间的分配系数为0.67。
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本文引用的文献
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Demonstration of a geometric isomer of bilirubin-IX alpha in the serum of a hyperbilirubinaemic newborn infant and the mechanism of jaundice phototherapy.一名高胆红素血症新生儿血清中胆红素-IXα几何异构体的证实及黄疸光疗机制
Biochem J. 1980 Sep 15;190(3):533-6. doi: 10.1042/bj1900533.
2
Concerning the structure of photobilirubin II.关于光胆红素II的结构。
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3
Mechanism of development of bronze baby syndrome in neonates treated with phototherapy.接受光疗的新生儿青铜色婴儿综合征的发病机制。
Pediatrics. 1982 Mar;69(3):273-6.
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Photochemistry of bilirubin.胆红素的光化学
Experientia. 1971 Oct 15;27(10):1147-9. doi: 10.1007/BF02286889.
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Preparation and properties of bilirubin photoisomers.胆红素光异构体的制备及性质
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