Stoll M S, Zenone E A, Ostrow J D, Zarembo J E
Biochem J. 1979 Oct 1;183(1):139-46. doi: 10.1042/bj1830139.
Polar photoisomers of bilirubin were formed by irradiation of bilirubin in chloroform solution in the absence of O2. Two pairs of compounds were isolated with molecular weights identical with bilirubin. One pair reverted to bilirubin in polar media and gave chemical reactions similar to bilirubin; the other pair were not reconverted into bilirubin by chemical means and gave reactions distinct from those of bilirubin. However, both groups were reconverted into bilirubin by irradiation in chloroform solution in the absence of O2. The probable role of these photoisomers in the catabolism of bilirubin during phototherapy of neonatal jaundice is discussed.
在无氧条件下，通过照射氯仿溶液中的胆红素形成了胆红素的极性光异构体。分离出了两对分子量与胆红素相同的化合物。其中一对在极性介质中会还原为胆红素，并给出与胆红素相似的化学反应；另一对不能通过化学方法再转化为胆红素，且给出与胆红素不同的反应。然而，在无氧条件下，通过照射氯仿溶液，这两组化合物都能再转化为胆红素。本文讨论了这些光异构体在新生儿黄疸光疗期间胆红素分解代谢中的可能作用。
