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空肠弯曲菌和结肠弯曲菌菌株之间的DNA相关性,这些菌株具有不同的血清群和马尿酸盐反应。

DNA relatedness among strains of Campylobacter jejuni and Campylobacter coli with divergent serogroup and hippurate reactions.

作者信息

Hébert G A, Edmonds P, Brenner D J

出版信息

J Clin Microbiol. 1984 Jul;20(1):138-40. doi: 10.1128/jcm.20.1.138-140.1984.

DOI:10.1128/jcm.20.1.138-140.1984
PMID:6746886
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC271267/
Abstract

Eleven strains of Campylobacter from earlier fluorescent-antibody studies were examined by DNA hybridization to determine their species. Three of the strains hydrolyzed sodium hippurate, and eight did not. Four of the hippurate-negative strains were in Campylobacter jejuni serogroups, and the remaining strains were in both C. jejuni and Campylobacter coli serogroups. DNA relatedness to type strains of C. jejuni and C. coli indicated that all three of the hippurate-positive strains and two of the hippurate-negative strains were C. jejuni. The six remaining hippurate-negative strains were C. coli. Two of the hippurate-negative strains in C. jejuni serogroups were C. jejuni, and two were C. coli. Three of the strains in serogroups of both species were C. jejuni, and four were C. coli. These studies confirm that a few strains of C. jejuni are hippurate negative and show that identical or highly related antigens are found in C. coli and C. jejuni.

摘要

对早期荧光抗体研究中的11株弯曲杆菌进行了DNA杂交检测,以确定它们所属的菌种。其中3株菌株能水解马尿酸钠,8株不能。4株马尿酸盐阴性菌株属于空肠弯曲菌血清群,其余菌株则同时属于空肠弯曲菌和结肠弯曲菌血清群。与空肠弯曲菌和结肠弯曲菌标准菌株的DNA相关性表明,所有3株马尿酸盐阳性菌株和2株马尿酸盐阴性菌株为空肠弯曲菌。其余6株马尿酸盐阴性菌株为结肠弯曲菌。空肠弯曲菌血清群中的2株马尿酸盐阴性菌株为空肠弯曲菌,2株为结肠弯曲菌。同时属于这两个菌种血清群的3株菌株为空肠弯曲菌,4株为结肠弯曲菌。这些研究证实,少数空肠弯曲菌菌株为马尿酸盐阴性,并表明在结肠弯曲菌和空肠弯曲菌中发现了相同或高度相关的抗原。

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