Short-term subcutaneous insulin infusion in diabetic children. Comparison with three daily insulin injections.

Sixteen insulin-dependent diabetic children and adolescents were studied on intensified insulin treatment (3II) and during continuous subcutaneous insulin infusion (CSII). Mean blood glucose, M-value and 24-h glycosuria were similar in both types of treatment. Symptomatic hypoglycemia occurred more often in patients on 3II than CSII. With 3II we observed blood glucose peaks early in the morning confirming that better overnight control can be achieved by CSII.