Mengel H, Karlog O
Acta Pharmacol Toxicol (Copenh). 1980 Jan;46(1):25-31. doi: 10.1111/j.1600-0773.1980.tb02414.x.
In a 5 weeks' study rats were given mercuric, methoxyethyl mercury and methyl mercury alone or together with sodium selenite. The distribution of mercury and selenium among the soluble proteins of liver and kidneys has been investigated by gel chromatography. Estimates of the ratios of the concentration of mercury (selenium) of the soluble proteins to that of the precipitates of liver and kidney homogenates are reported. The ratios seem to decrease when selenium is given concomitant with mercury. When mercuric chloride was given alone, 50% of the mercury content in the soluble kidney proteins was found in the fractions of proteins with a molecular weight similar to that of metallothionein. No mercury could be detected in these fractions when both mercuric chloride and sodium selenite were given.
在一项为期5周的研究中，给大鼠单独或与亚硒酸钠一起给予汞、甲氧基乙基汞和甲基汞。通过凝胶色谱法研究了汞和硒在肝脏和肾脏可溶性蛋白质中的分布。报告了肝脏和肾脏匀浆可溶性蛋白质中汞（硒）浓度与沉淀物中汞（硒）浓度之比的估计值。当硒与汞同时给予时，该比值似乎会降低。单独给予氯化汞时，在肾脏可溶性蛋白质中，50%的汞含量存在于分子量与金属硫蛋白相似的蛋白质组分中。当同时给予氯化汞和亚硒酸钠时，在这些组分中未检测到汞。
