Marshall R B, BAskerville A, Hambleton P, Adams G D
Br J Exp Pathol. 1980 Apr;61(2):124-31.
Grivet monkeys experimentally infected with Leptospira interrogans serovars balcanica and tarassovi showed no clinical disease, but severe meningoencephalitis was demonstrated histologically in animals killed 26 and 33 days after infection. The meningeal and perivascular reactions were exclusively lymphocytic. Mild focal lesions of degeneration and cellular infiltration were also present in the kidneys and femoral musculature.
实验感染问号钩端螺旋体巴尔干尼亚血清型和塔拉索夫血清型的狮尾猴未表现出临床疾病,但在感染后26天和33天处死的动物中,组织学检查显示有严重的脑膜脑炎。脑膜和血管周围反应均为淋巴细胞性。肾脏和股部肌肉也有轻度局灶性变性和细胞浸润病变。