用问号钩端螺旋体哈焦血清型对猴子进行实验性感染。
Experimental infection of monkeys with Leptospira interrogans serovar hardjo.
作者信息
Palmer M F, Waitkins S A, Fitzgeorge R B, Baskerville A
出版信息
Epidemiol Infect. 1987 Apr;98(2):191-7. doi: 10.1017/s0950268800061902.
Abstract
Grivet monkeys experimentally infected with two different strains of Leptospira interrogans serovar hardjo showed no signs of severe clinical disease. There were no significant macroscopic lesions in any of the tissues examined, but the organisms were demonstrated in various tissues by immunofluorescent technique and were isolated from the blood and urine of two monkeys and the kidney of one. Abraded skin was shown to be a viable route of infection in non-human primates.
摘要
实验感染两种不同问号钩端螺旋体哈焦血清型菌株的狮尾狒没有出现严重临床疾病的迹象。在所检查的任何组织中均未发现明显的宏观病变，但通过免疫荧光技术在各种组织中检测到了病原体，并且从两只猴子的血液和尿液以及一只猴子的肾脏中分离出了病原体。在非人灵长类动物中，破损皮肤被证明是一种可行的感染途径。
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