Santon J B, Pellegrini M
Proc Natl Acad Sci U S A. 1980 Oct;77(10):5649-53. doi: 10.1073/pnas.77.10.5649.
Newly synthesized ribosomal proteins (r-proteins) are found associated with ribosomal subunits as soon as 90 min after fertilization of Drosophila melanogaster embryos. This event substantially precedes the blastoderm stage of embryonic development, at which time the synthesis of rRNA begins. At the preblastoderm stage, embryos synthesize many and possibly all of the r-proteins, although only a small subset of these is incorporated onto ribosomes, presumably by addition or exchange onto preexisting ribosomes. After blastoderm formation, all of the newly synthesized r-proteins along with newly synthesized rRNA are incorporated into ribosomal subunits.
在黑腹果蝇胚胎受精后90分钟，新合成的核糖体蛋白（r蛋白）就会与核糖体亚基结合。这一事件大大早于胚胎发育的囊胚期，而囊胚期时rRNA才开始合成。在前囊胚期，胚胎会合成许多甚至可能是所有的r蛋白，尽管其中只有一小部分会结合到核糖体上，推测是通过添加到或交换到预先存在的核糖体上。囊胚形成后，所有新合成的r蛋白以及新合成的rRNA都会被整合到核糖体亚基中。
