Johnson A P, Clark J B, Osborn M F, Taylor-Robinson D
Br J Exp Pathol. 1980 Oct;61(5):521-7.
Organ cultures of human and guinea-pig genital mucosa were inoculated with Neisseria gonorrhoeae, and the association of the bacteria with the epithelial surface of each tissue was studied by light microscopy and by scanning electron microscopy. Gonococci attached to the mucosa of human fallopian tube, adhering specifically to the surface of non-ciliated epithelial cells. In contrast, gonococci rarely attached to the mucosal surface of guinea-pig uterine horn, vagina or bladder, although organisms were occasionally seen associated with the submucosal tissue in areas where the epithelium had sloughed, and in extracellular mucus secretions. There is no evidence from this study that gonococci adhere to guinea-pig tissue in a manner analogous to that seen with human genital tissue.
用人和豚鼠生殖黏膜的器官培养物接种淋病奈瑟菌，通过光学显微镜和扫描电子显微镜研究细菌与各组织上皮表面的关联。淋球菌附着于人类输卵管黏膜，特异性地黏附于非纤毛上皮细胞表面。相比之下，淋球菌很少附着于豚鼠子宫角、阴道或膀胱的黏膜表面，尽管在上皮已脱落的区域以及细胞外黏液分泌物中偶尔可见细菌与黏膜下组织相关联。这项研究没有证据表明淋球菌以类似于在人类生殖组织中所见的方式附着于豚鼠组织。
