阿米卡星的脑脊液穿透情况。
Cerebrospinal fluid penetration of amikacin.
作者信息
Briedis D J, Robson H G
出版信息
Antimicrob Agents Chemother. 1978 Jun;13(6):1042-3. doi: 10.1128/AAC.13.6.1042.
Abstract
Adult volunteers underwent a single lumbar puncture 1 to 8.5 h after one 7.5-mg/kg intramuscular amikacin injection. Eighteen showed no detectable drug in cerebrospinal fluid; six had concentrations <0.5 mug/ml.
摘要
成年志愿者在肌肉注射7.5毫克/千克阿米卡星1至8.5小时后接受了单次腰椎穿刺。18人脑脊液中未检测到药物；6人的浓度<0.5微克/毫升。
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