Suzuki J, Tanaka S, Yoshimoto T
Surg Neurol. 1980 Dec;14(6):467-72.
Using the incomplete cerebral hemisphere infarction model in dogs, observations were made on the effect of 20% mannitol on brain swelling in groups of experimental animals following recirculation. In dogs undergoing 2-hour occlusion, mannitol clearly suppresses subsequent swelling; but after 6-hour occlusion, it was found that mannitol alone had little positive effect.
利用犬不完全性脑半球梗死模型，对20%甘露醇在再灌注后对实验动物组脑肿胀的影响进行了观察。在闭塞2小时的犬中，甘露醇明显抑制随后的肿胀；但在闭塞6小时后，发现单独使用甘露醇几乎没有积极作用。
