地贝卡星与庆大霉素活性的体外比较。
In vitro comparison of dibekacin and gentamicin activities.
作者信息
Hill C D, Counts G W, Turck M
出版信息
Antimicrob Agents Chemother. 1981 Jan;19(1):190-2. doi: 10.1128/AAC.19.1.190.
Abstract
Dibekacin, a new parenteral aminoglycoside, was compared with gentamicin in vitro against 221 clinical isolates. Tests for minimum inhibitory concentrations, performed in agar, demonstrated that dibekacin was comparable to gentamicin against most isolates tested. Dibekacin was slightly more active than gentamicin against some isolates of Pseudomonas aeruginosa, but was significantly less active against strains of Serratia.
摘要
地贝卡星是一种新型肠道外氨基糖苷类抗生素，在体外将其与庆大霉素针对221株临床分离菌进行了比较。在琼脂中进行的最低抑菌浓度测试表明，地贝卡星对大多数测试分离菌的抗菌活性与庆大霉素相当。地贝卡星对某些铜绿假单胞菌分离株的活性略高于庆大霉素，但对沙雷氏菌属菌株的活性则显著低于庆大霉素。
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