Makler A, Urbach Y, Lefler E, Merzbach D
Fertil Steril. 1981 Jun;35(6):666-70. doi: 10.1016/s0015-0282(16)45562-7.
The influence of bacterial growth on human sperm motility and viability was evaluated objectively with the multiple-exposure photography method. Experimental semen specimens, obtained from normal donors bh nonaseptic means of masturbation, were incubated with antibiotics at room temperature or body temperature for 24 hours. Although bacteria, grew in control specimens, were totally eradicated in all antibiotic-treated specimens, no significant difference was found between these groups with regard to sperm motility throughout the time of incubation. Sperm survival was not inhibited, nor was it extended as a result of suppression of bacterial growth. In both groups, survival time was much shorter in specimens incubated at body temperature than in those kept at room temperature. Sperm motility was not affected after 2 hours of incubation of fresh specimens with concentrations of various pathogenic bacteria similar to those found in severe prostatitis. The question of whether the use of antibiotics in the treatment of asthenospermia per se has a prognostic value is discussed.
采用多次曝光摄影法客观评估了细菌生长对人类精子活力和生存能力的影响。通过非无菌手淫方式从正常供体获取实验精液标本，将其在室温或体温下与抗生素孵育24小时。尽管对照标本中生长的细菌在所有抗生素处理的标本中被完全根除，但在整个孵育期间，这些组之间在精子活力方面未发现显著差异。精子存活未受到抑制，也未因细菌生长的抑制而延长。在两组中，体温下孵育的标本存活时间比室温下保存的标本短得多。新鲜标本与浓度类似于严重前列腺炎中发现的各种病原菌孵育2小时后，精子活力未受影响。文中讨论了在弱精子症治疗中使用抗生素本身是否具有预后价值的问题。
