Grimes D S, Goddard J
Br Med J. 1978 Aug 12;2(6135):460-1. doi: 10.1136/bmj.2.6135.460.
Gastric emptying after a test meal was studied in 17 normal volunteers--10 habitual smokers and seven non-smokers. The solid component of the test meal was labelled with technetium and the liquid component with indium. After one meal the habitual smokers smoked two cigarettes. Emptying curves were produced for both technetium and indium, and the differences between curves for meals with and without cigarettes were analysed. Cigarette smoking accelerated the rate at which the liquid component of a meal left the stomach. This may be important in the pathogenesis of duodneal ulcer and the delay in healing caused by cigarette smoking.
在17名正常志愿者(10名习惯性吸烟者和7名不吸烟者)中研究了试餐后的胃排空情况。试餐的固体成分用锝标记,液体成分用铟标记。在一餐之后,习惯性吸烟者吸了两支香烟。分别生成了锝和铟的排空曲线,并分析了有无吸烟情况下餐食排空曲线的差异。吸烟加快了餐食液体成分离开胃的速度。这在十二指肠溃疡的发病机制以及吸烟导致的愈合延迟中可能具有重要意义。