愈合期与非愈合期压疮溃疡微生物菌群的调查研究。
Investigation into the microbial flora of healing and non-healing decubitus ulcers.
作者信息
Daltrey D C, Rhodes B, Chattwood J G
出版信息
J Clin Pathol. 1981 Jul;34(7):701-5. doi: 10.1136/jcp.34.7.701.
Abstract
Seventy-four pressure lesions in fifty-three geriatric patients were observed at weekly intervals to determine the bacterial flora and the healing index of each lesion, expressed as initial area of lesion (cm2) - final area of lesion (cm2) divided by time in days. The micro-organisms which caused infection included Staphylococcus aureus, Proteus mirabilis, Pseudomonas aeruginosa, Bacteroides fragilis and Bacteroides asaccharolyticus. Many lesions contained a mixed flora. P mirabilis and Ps aeruginosa were associated with necrotic (p less than 0.005) and enlarging (p less than 5 x 10(-7)) lesions. Bacteroides spp were associated with necrotic lesions (p less than 0.05). The presence of S aureus in a lesion was not associated with any particular trend in healing index. The implications of the microbiological findings are discussed.
摘要
对53名老年患者的74处压疮每周进行一次观察，以确定每个压疮的细菌菌群和愈合指数，愈合指数的计算方式为（初始疮面面积（平方厘米）-最终疮面面积（平方厘米））除以天数。引起感染的微生物包括金黄色葡萄球菌、奇异变形杆菌、铜绿假单胞菌、脆弱拟杆菌和不解糖拟杆菌。许多压疮含有混合菌群。奇异变形杆菌和铜绿假单胞菌与坏死性压疮（p<0.005）及面积扩大的压疮（p<5×10⁻⁷）有关。拟杆菌属与坏死性压疮有关（p<0.05）。疮面中金黄色葡萄球菌的存在与愈合指数的任何特定趋势均无关联。文中讨论了微生物学研究结果的意义。
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