Bonavina Luigi, Bona Davide, Abraham Medhanie, Saino Greta, Abate Emmanuele
University of Milano, Department of Medical and Surgical Sciences, Section of General Surgery, IRCCS Policlinico, San Donato, Italy.
World J Gastroenterol. 2007 May 14;13(18):2586-9. doi: 10.3748/wjg.v13.i18.2586.
To assess the effectiveness of minimally invasive versus traditional open surgical approach in the treatment of Zenker diverticulum.
Between 1976 and 2006, 297 patients underwent transoral stapling (n = 181) or stapled diverticulectomy and cricopharyngeal myotomy (n = 116). Subjective and objective evaluations of the outcome of the two procedures were made at 1 and 6 mo after operation, and then every year. Long-term follow-up data were available for a subgroup of patients at a minimum of 5 and 10 years.
The operative time and hospital stay were markedly reduced in patients undergoing the endosurgical approach. Overall, 92% of patients undergoing the endosurgical approach and 94% of those undergoing the open approach were symptom-free or were significantly improved after a median follow-up of 27 and 48 mo, respectively. At a minimum follow-up of 5 and 10 years, most patients were asymptomatic after both procedures, except for those individuals undergoing an endosurgical procedure for a small diverticulum (< 3 cm).
Both operations relieve the outflow obstruction at the pharyngoesophageal junction, indicating that cricopharyngeal myotomy has an important therapeutic role in this disease independent of the resection of the pouch and of the surgical approach. Diverticula smaller than 3 cm represent a formal contraindication to the endosurgical approach because the common wall is too short to accommodate one cartridge of staples and to allow complete division of the sphincter.
评估微创与传统开放手术方法治疗Zenker憩室的有效性。
1976年至2006年间,297例患者接受了经口吻合术(n = 181)或吻合器憩室切除术及环咽肌切开术(n = 116)。在术后1个月和6个月时对两种手术结果进行主观和客观评估,之后每年评估一次。对部分患者进行了至少5年和10年的长期随访。
接受内镜手术的患者手术时间和住院时间明显缩短。总体而言,经内镜手术的患者中有92%,开放手术的患者中有94%在分别进行了27个月和48个月的中位随访后症状消失或明显改善。在至少5年和10年的随访中,除了因小憩室(< 3 cm)接受内镜手术的患者外,大多数患者在两种手术后均无症状。
两种手术均缓解了咽食管交界处的流出道梗阻,这表明环咽肌切开术在该病治疗中具有重要治疗作用,与憩室切除及手术方式无关。小于3 cm的憩室是内镜手术的正式禁忌证,因为共同壁太短,无法容纳一钉仓吻合器,也无法完全切开括约肌。