Nishizumi M
Gan. 1980 Dec;71(6):910-2.
A potent hepatocarcinogen, diethylnitrosamine (DEN), was orally administered at 50 ppm for 5 weeks to Wistar rats preexposed to polychlorinated biphenyls (PCB) in utero and via mother's milk. The numbers of liver tumors induced by administration of DEN were significantly reduced in the rats exposed to PCB in an early stage of life, compared with control rats. This tumor-inhibiting action was particularly clear in male offspring.
一种强效肝癌致癌物二乙基亚硝胺（DEN），以50 ppm的浓度口服给药5周，用于喂养在子宫内和通过母乳预先接触多氯联苯（PCB）的Wistar大鼠。与对照大鼠相比，在生命早期接触PCB的大鼠中，给予DEN诱导的肝肿瘤数量显著减少。这种肿瘤抑制作用在雄性后代中尤为明显。
