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接触多氯联苯或苯巴比妥可增强二乙基亚硝胺诱导的大鼠肝癌发生。

Enhancement of diethylnitrosamine hepatocarcinogenesis in rats by exposure to polychlorinated biphenyls or phenobarbital.

作者信息

Nishizumi M

出版信息

Cancer Lett. 1976 Sep;2(1):11-5. doi: 10.1016/s0304-3835(76)80004-3.

DOI:10.1016/s0304-3835(76)80004-3
PMID:189905
Abstract

Diethylnitrosamine (DENA) hepatocarcinogenesis was enhanced by sequential exposure with polychlorinated biphenyls (PCBs) and with phenobarbital. This was shown by the earlier appearance of tumors and a significant increase in the number of tumors. However, there was no evidence suggesting an acceleration of tumor growth.

摘要

二乙基亚硝胺（DENA）诱导的肝癌发生通过多氯联苯（PCBs）和苯巴比妥的序贯暴露得以增强。这表现为肿瘤更早出现以及肿瘤数量显著增加。然而，没有证据表明肿瘤生长加速。

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Enhancement of diethylnitrosamine hepatocarcinogenesis in rats by exposure to polychlorinated biphenyls or phenobarbital.接触多氯联苯或苯巴比妥可增强二乙基亚硝胺诱导的大鼠肝癌发生。
Cancer Lett. 1976 Sep;2(1):11-5. doi: 10.1016/s0304-3835(76)80004-3.
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