Dvoretskiĭ D P
Fiziol Zh SSSR Im I M Sechenova. 1981 Aug;67(8):1229-36.
In acute experiments on cats responses of the lung vessels to hypoxic and hypercapnic stimuli and the latters effect on minor circle hemodynamics were studied as well as the role of changes of the blood acid-alkaline balance and volume of ventilation in potentiation and blocking of the above responses. The alveolar hypoxia and hypercapnia being induced a reversed dependence between the relative mass of the lung area and reduction of its blood flow vasdseined Hyperventilation with hypoxic gas mixture inhibited the hypoxic vasoconstriction in respective lung area which seems to suggest a shift towards alkalosis of the blood in the area of gases respiratory diffusion. The autoregulation of the lung gas exchange is supposed to be the function of the respiratory dead space.
在对猫进行的急性实验中，研究了肺血管对缺氧和高碳酸血症刺激的反应以及后者对微循环血流动力学的影响，还研究了血液酸碱平衡变化和通气量在上述反应的增强和阻断中的作用。诱导肺泡缺氧和高碳酸血症后，肺区域相对质量与其血流减少之间存在反向依赖关系。用缺氧气体混合物进行过度通气可抑制相应肺区域的缺氧性血管收缩，这似乎表明气体呼吸扩散区域的血液向碱中毒转变。肺气体交换的自动调节被认为是呼吸死腔的功能。
