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相似文献

1
DR antigens and rheumatoid arthritis: a study of two populations.DR 抗原与类风湿性关节炎：对两个群体的研究。
Br Med J (Clin Res Ed). 1981 Nov 14;283(6302):1287-8. doi: 10.1136/bmj.283.6302.1287.
2
Is rheumatoid arthritis in Indians associated with HLA antigens sharing a DR beta 1 epitope?印度人的类风湿性关节炎是否与共享DRβ1表位的HLA抗原相关？
Ann Rheum Dis. 1991 May;50(5):295-7. doi: 10.1136/ard.50.5.295.
3
HLA-DR antigens in rheumatoid arthritis. A Swiss collaborative study. Swiss Federal Commission for the Rheumatic Diseases, Subcommission for Research.类风湿关节炎中的HLA - DR抗原。一项瑞士合作研究。瑞士联邦风湿病委员会，研究小组委员会
Rheumatol Int. 1981;1(3):111-3.
4
HLA-DR antigens and disease patterns of rheumatoid arthritis.HLA - DR抗原与类风湿关节炎的疾病模式
Rheumatol Int. 1983;3(3):113-6. doi: 10.1007/BF00541190.
5
[HLA-A, B, C, and DR typing in rheumatoid polyarthritis].
Rev Med Interne. 1984 Jun;5(2):128-35. doi: 10.1016/s0248-8663(84)80035-1.
6
HLA-DR antigens in Blacks with rheumatoid arthritis and systemic lupus erythematosus.患有类风湿性关节炎和系统性红斑狼疮的黑人中的HLA - DR抗原
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7
Association of HLA-Aw31 and HLA-DR1 with adult rheumatoid arthritis.HLA-Aw31和HLA-DR1与成人类风湿性关节炎的关联。
Ann Rheum Dis. 1982 Aug;41(4):403-4. doi: 10.1136/ard.41.4.403.
8
[HLA-DR in rheumatoid arthritis].
Ter Arkh. 1985;57(8):80-2.
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HLA-DR antigens in rheumatoid arthritis in North India.印度北部类风湿关节炎中的人类白细胞抗原-DR抗原
Tissue Antigens. 1982 Oct;20(4):300-2. doi: 10.1111/j.1399-0039.1982.tb00360.x.

引用本文的文献

1
Antibacterial and antipeptide antibodies in Japanese and Finnish patients with rheumatoid arthritis.日本和芬兰类风湿性关节炎患者体内的抗菌抗体和抗肽抗体
Clin Rheumatol. 2004 Apr;23(2):134-41. doi: 10.1007/s10067-003-0847-6. Epub 2004 Feb 13.
2
Polyclonal antibody directed against human RANTES ameliorates disease in the Lewis rat adjuvant-induced arthritis model.针对人趋化因子调节激活正常T细胞表达和分泌因子（RANTES）的多克隆抗体可改善Lewis大鼠佐剂诱导性关节炎模型中的疾病。
J Clin Invest. 1998 Jun 15;101(12):2910-9. doi: 10.1172/JCI2172.
3
T cell receptor V beta gene bias in rheumatoid arthritis.类风湿关节炎中T细胞受体Vβ基因偏向性
J Clin Invest. 1993 Dec;92(6):2688-701. doi: 10.1172/JCI116886.
4
Rheumatoid arthritis in a population sample in the Gulf: clinical observations.海湾地区人群样本中的类风湿性关节炎：临床观察
Clin Rheumatol. 1993 Dec;12(4):506-10. doi: 10.1007/BF02231780.
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HLA class II and T-cell receptor beta chain polymorphisms in Belgian patients with rheumatoid arthritis: no evidence for disease association with the TCRBC2, TCRBV8 and TCRBV11 polymorphisms.比利时类风湿性关节炎患者的HLA II类分子和T细胞受体β链多态性：无证据表明疾病与TCRBC2、TCRBV8和TCRBV11多态性相关。
Ann Rheum Dis. 1994 Sep;53(9):580-6. doi: 10.1136/ard.53.9.580.
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HLA-linked rheumatoid arthritis.HLA相关的类风湿关节炎。
Am J Hum Genet. 1994 Oct;55(4):738-46.
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Anti-neutrophil cytoplasm antibodies (ANCA) in rheumatoid arthritis: relationship to HLA-DR phenotypes, rheumatoid factor, anti-nuclear antibodies and disease severity.类风湿关节炎中的抗中性粒细胞胞浆抗体（ANCA）：与HLA - DR表型、类风湿因子、抗核抗体及疾病严重程度的关系
Rheumatol Int. 1994;14(4):155-61. doi: 10.1007/BF00579701.
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The specificity of the anti-Proteus antibody response in tissue-typed rheumatoid arthritis (RA) patients from Brest.
Rheumatol Int. 1995;15(2):79-82. doi: 10.1007/BF00262713.
9
Evidence for an association between rheumatoid arthritis and autoimmune endocrine disease.类风湿性关节炎与自身免疫性内分泌疾病之间关联的证据。
Ann Rheum Dis. 1983 Jun;42(3):297-300. doi: 10.1136/ard.42.3.297.
10
Penicillamine-induced myasthenia in rheumatoid arthritis: its clinical and genetic features.青霉胺诱发的类风湿关节炎伴重症肌无力：临床及遗传学特征
Ann Rheum Dis. 1983 Oct;42(5):500-4. doi: 10.1136/ard.42.5.500.

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The estimation and significance of the logarithm of a ratio of frequencies.频率比的对数的估计及其意义。
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[Association of HLA-DR and adult rheumatoid polyarthritis in southern France].
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Rheumatoid arthritis and B lymphocyte alloantigen HLA-DRw4.类风湿性关节炎与B淋巴细胞同种抗原HLA - DRw4
J Rheumatol. 1980 Jan-Feb;7(1):9-12.
4
Association of HLA-DRw4 with rheumatoid arthritis in black and white patients.HLA-DRw4与黑种人和白种人类风湿关节炎的关联。
Arthritis Rheum. 1980 Nov;23(11):1241-5. doi: 10.1002/art.1780231102.
5
Simultaneous detection of two cell populations by two-colour fluorescence and application to the recognition of B-cell determinants.通过双色荧光同时检测两种细胞群体及其在B细胞决定簇识别中的应用。
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6
Genetic basis of rheumatoid disease: HLA antigens, disease manifestations, and toxic reactions to drugs.类风湿病的遗传基础：HLA抗原、疾病表现及对药物的毒性反应。
Br Med J. 1978 Nov 11;2(6148):1326-8. doi: 10.1136/bmj.2.6148.1326.
7
Structural studies of murine I-E and human DR antigens.小鼠I-E和人类DR抗原的结构研究。
Mol Immunol. 1979 Jan;16(1):37-42. doi: 10.1016/0161-5890(79)90025-7.
8
Association of the B-cell alloantigen DRw4 with rheumatoid arthritis.B细胞同种异体抗原DRw4与类风湿性关节炎的关联。
N Engl J Med. 1978 Apr 20;298(16):869-71. doi: 10.1056/NEJM197804202981602.

DR 抗原与类风湿性关节炎：对两个群体的研究。

DR antigens and rheumatoid arthritis: a study of two populations.

作者信息

Woodrow J C, Nichol F E, Zaphiropoulos G

出版信息

Br Med J (Clin Res Ed). 1981 Nov 14;283(6302):1287-8. doi: 10.1136/bmj.283.6302.1287.

DOI:10.1136/bmj.283.6302.1287
PMID:6794822
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1507681/
Abstract

Thr prevalence of HLA-DR antigens was determined in a group of white patients with rheumatoid arthritis, similar patients originating from the Indian subcontinent, and corresponding controls. Rheumatoid arthritis was found to be highly associated with DR4 in the white patients but with DR1 in the Indian patients. These results raise the possibility that the DR antigens themselves do not play a part in increasing susceptibility to rheumatoid arthritis, but the locus for increased susceptibility is probably closely linked to the DR locus.

摘要

测定了一组患类风湿性关节炎的白人患者、来自印度次大陆的类似患者以及相应对照组中HLA - DR抗原的患病率。结果发现，类风湿性关节炎在白人患者中与DR4高度相关，而在印度患者中与DR1相关。这些结果增加了一种可能性，即DR抗原本身在增加类风湿性关节炎易感性方面并不起作用，但易感性增加的基因座可能与DR基因座紧密连锁。