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电容器制造行业从业人员体内多氯联苯的负荷量

Body burden of polychlorinated biphenyls among persons employed in capacitor manufacturing.

作者信息

Wolff M S, Fischbein A, Thornton J, Rice C, Lilis R, Selikoff I J

出版信息

Int Arch Occup Environ Health. 1982 Feb;49(3-4):199-208. doi: 10.1007/BF00377929.

Abstract

In an effort to assess exposure among workers engaged in capacitors manufacture, PCB concentration was determined in plasma (290) and adipose tissue (61). In general, males had higher concentrations of PCBs than females. The correlation of plasma concentration (1-546 ppb) of the more highly chlorinated PCBs, which had been used in past, with total duration of employment suggested accumulation over time. The gc-ec pattern of these PCB peaks was, in most cases, characteristic of exposure to a PCB mixture with 54% chlorine. The less highly chlorinated PCBs, di-, tri-, and tetrachlorobiphenyls, were the source of current exposure, and were observed in concentrations of 6-2530 ppb in plasma. Higher exposure occurred among persons with direct contact with PCBs in jobs such as capacitor filling. Adipose tissue concentrations, for both the more highly chlorinated PCBs (1-165 ppm) and lower chlorinated PCBs (0.6-414 ppm), were proportional to those in plasma.

摘要

为了评估从事电容器制造的工人的接触情况,测定了血浆(290例)和脂肪组织(61例)中的多氯联苯浓度。一般来说,男性的多氯联苯浓度高于女性。过去使用的氯化程度较高的多氯联苯的血浆浓度(1 - 546 ppb)与总就业时长之间的相关性表明其会随时间积累。在大多数情况下,这些多氯联苯峰的气相色谱 - 电子捕获模式是接触含54%氯的多氯联苯混合物的特征。氯化程度较低的多氯联苯,即二氯、三氯和四氯联苯,是当前接触的来源,在血浆中的浓度为6 - 2530 ppb。在诸如电容器填充等工作中直接接触多氯联苯的人员中接触程度较高。脂肪组织中,氯化程度较高的多氯联苯(1 - 165 ppm)和氯化程度较低的多氯联苯(0.6 - 414 ppm)的浓度与血浆中的浓度成正比。

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