Clark J E, Ragsdale S W, Ljungdahl L G, Wiegel J
J Bacteriol. 1982 Jul;151(1):507-9. doi: 10.1128/jb.151.1.507-509.1982.
The acetogenic bacterium Clostridium thermoautotrophicum, grown on methanol, glucose, or CO2-H2, contained high levels of corrinoids, formate dehydrogenase, tetrahydrofolate enzymes, carbon monoxide dehydrogenase, and hydrogenase. Cell-free extracts catalyzed pyruvate-dependent formation of acetate from methyltetrahydrofolate. These results suggest that C. thermoautotrophicum synthesizes acetate from CO2 via a formate-tetrahydrofolate-corrinoid pathway.
在甲醇、葡萄糖或CO₂-H₂上生长的产乙酸细菌热自养梭菌含有高水平的类咕啉、甲酸脱氢酶、四氢叶酸酶、一氧化碳脱氢酶和氢化酶。无细胞提取物催化了从甲基四氢叶酸依赖丙酮酸形成乙酸盐的过程。这些结果表明，热自养梭菌通过甲酸-四氢叶酸-类咕啉途径从CO₂合成乙酸盐。
