口服过量铁剂后由小肠结肠炎耶尔森菌引起的败血症。
Septicaemia due to Yersinia enterocolitica after oral overdoses of iron.
作者信息
Melby K, Slørdahl S, Gutteberg T J, Nordbø S A
出版信息
Br Med J (Clin Res Ed). 1982 Aug 14;285(6340):467-8. doi: 10.1136/bmj.285.6340.467.
Abstract
Septicaemia occurred after accidental oral overdoses of iron in two previously healthy children. Yersinia enterocolitica serotype 0:3 was recovered from blood and stool cultures in both patients. Enhanced growth of Y enterocolitica in the intestine combined with damage of intestinal mucosa may have been of major importance for the development of generalised infection in these cases. Iron and the iron chelating agent desferrioxamine may possibly have a pathogenetic role in such circumstances.
摘要
两名原本健康的儿童在意外经口过量摄入铁剂后发生了败血症。从两名患者的血液和粪便培养物中均分离出了小肠结肠炎耶尔森菌0:3血清型。在这些病例中，小肠结肠炎耶尔森菌在肠道内的生长增强以及肠黏膜损伤可能对全身性感染的发生起了主要作用。在这种情况下，铁和铁螯合剂去铁胺可能具有致病作用。
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