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1
Septicaemia due to Yersinia enterocolitica after oral overdoses of iron.口服过量铁剂后由小肠结肠炎耶尔森菌引起的败血症。
Br Med J (Clin Res Ed). 1982 Aug 14;285(6340):467-8. doi: 10.1136/bmj.285.6340.467.
2
Yersiniosis in acutely iron-loaded children treated with desferrioxamine.接受去铁胺治疗的急性铁负荷过重儿童的耶尔森菌病。
J Antimicrob Chemother. 1988 May;21(5):680-1. doi: 10.1093/jac/21.5.680.
3
Iron sepsis: Yersinia enterocolitica septicemia possibly caused by an overdose of iron.铁中毒败血症：小肠结肠炎耶尔森菌败血症可能由铁摄入过量引起。
N Engl J Med. 1987 Apr 23;316(17):1092-3.
4
Fatal Yersinia enterocolitica sepsis after blood transfusion.输血后致命性小肠结肠炎耶尔森菌败血症
Arch Pathol Lab Med. 1985 Nov;109(11):1040-2.
5
[Roles of iron overload and chelating treatment in Yersinia infectious complicated by major thalassemia].[铁过载及螯合治疗在重型地中海贫血合并耶尔森菌感染中的作用]
Presse Med. 1987 Oct 3;16(32):1574-6.
6
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7
Septicemia due to Yersinia enterocolitica in a hemodialyzed, iron-depleted patient receiving omeprazole and oral iron supplementation.一名接受血液透析、缺铁且正在服用奥美拉唑和口服铁补充剂的患者发生小肠结肠炎耶尔森菌败血症。
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8
[Yersinia enterocolitica septicaemia associated with Yersinia intestinal lesions detected by colonoscopy (author's transl)].结肠镜检查发现耶尔森氏小肠结肠炎败血症与耶尔森氏肠道病变相关（作者译）
Nouv Presse Med. 1981 Dec 5;10(44):3639-41.
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[Case report: Yersinia enterocolitica septicemia in an American minipig].[病例报告：一只美国小型猪的小肠结肠炎耶尔森菌败血症]
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The first successful isolation and identification of Yersinia enterocolitica in Iran.伊朗首次成功分离并鉴定出小肠结肠炎耶尔森菌。
Contrib Microbiol Immunol. 1979;5:206-11.

引用本文的文献

1
Critical Role for Molecular Iron in Coxiella burnetii Replication and Viability.分子铁在贝氏柯克斯体复制和存活中的关键作用。
mSphere. 2020 Jul 22;5(4):e00458-20. doi: 10.1128/mSphere.00458-20.
2
Iron Metabolism at the Interface between Host and Pathogen: From Nutritional Immunity to Antibacterial Development.宿主与病原体之间的铁代谢：从营养免疫到抗菌发展。
Int J Mol Sci. 2020 Mar 20;21(6):2145. doi: 10.3390/ijms21062145.
3
Transition Metals and Virulence in Bacteria.过渡金属与细菌的毒力
Annu Rev Genet. 2016 Nov 23;50:67-91. doi: 10.1146/annurev-genet-120215-035146. Epub 2016 Sep 7.
4
Acute iron poisoning.急性铁中毒
Indian J Pediatr. 1997 Jul-Aug;64(4):485-93. doi: 10.1007/BF02737753.
5
Does occupational exposure to iron promote infection?职业性接触铁会促进感染吗？
Occup Environ Med. 1997 Aug;54(8):529-34. doi: 10.1136/oem.54.8.529.
6
Yersinia enterocolitica: the charisma continues.小肠结肠炎耶尔森菌：魅力依旧。
Clin Microbiol Rev. 1997 Apr;10(2):257-76. doi: 10.1128/CMR.10.2.257.
7
Role of iron in regulation of virulence genes.铁在毒力基因调控中的作用。
Clin Microbiol Rev. 1993 Apr;6(2):137-49. doi: 10.1128/CMR.6.2.137.
8
Experimental candidiasis in iron overload.铁过载中的实验性念珠菌病
Mycopathologia. 1985 Jan;89(1):59-63. doi: 10.1007/BF00437134.
9
Effects of iron and desferrioxamine on infections with Yersinia enterocolitica.铁和去铁胺对小肠结肠炎耶尔森菌感染的影响。
Infect Immun. 1985 Mar;47(3):774-9. doi: 10.1128/iai.47.3.774-779.1985.
10
Management of acute iron poisoning.急性铁中毒的处理
Med Toxicol. 1986 Mar-Apr;1(2):83-100. doi: 10.1007/BF03259830.

本文引用的文献

1
Deferoxamine in the treatment of acute iron poisoning. Clinical experiences with 172 children.去铁胺治疗急性铁中毒。172例儿童的临床经验。
Clin Pediatr (Phila). 1966 Sep;5(9):531-5. doi: 10.1177/000992286600500907.
2
Iron poisoning in children.儿童铁中毒
Clin Toxicol. 1975;8(6):575-97. doi: 10.3109/15563657508990084.
3
Generalized Yersinia enterocolitica infection.全身性小肠结肠炎耶尔森菌感染
J Infect Dis. 1975 Apr;131(4):447-51. doi: 10.1093/infdis/131.4.447.
4
Yersinia enterocolitica: a panoramic view of a charismatic microorganism.小肠结肠炎耶尔森菌：一种具有魅力的微生物的全景概述
CRC Crit Rev Microbiol. 1977;5(2):211-41. doi: 10.3109/10408417709102312.
5
Production of enterotoxin by Yersinia enterocolitica.小肠结肠炎耶尔森菌产生肠毒素。
Infect Immun. 1978 Mar;19(3):908-11. doi: 10.1128/iai.19.3.908-911.1978.
6
Increased incidence of gram-negative neonatal sepsis with intramuscula iron administration.肌肉注射铁剂会增加新生儿革兰氏阴性菌败血症的发病率。
Pediatrics. 1977 Dec;60(6):908-12.
7
Enteritis, abscess and septicaemia by Yersinia enterocolitica in a thalassaemic child.一名地中海贫血患儿感染小肠结肠炎耶尔森菌所致的肠炎、脓肿和败血症
Contrib Microbiol Immunol. 1979;5:292-7.
8
Generalized infection with Yersinia enterocolitica and the role of iron.小肠结肠炎耶尔森菌的全身性感染及铁的作用
Contrib Microbiol Immunol. 1979;5:277-82.
9
Iron and infection.铁与感染
Microbiol Rev. 1978 Mar;42(1):45-66. doi: 10.1128/mr.42.1.45-66.1978.
10
The adverse effect of iron repletion on the course of certain infections.铁补充对某些感染病程的不良影响。
Br Med J. 1978 Oct 21;2(6145):1113-5. doi: 10.1136/bmj.2.6145.1113.

口服过量铁剂后由小肠结肠炎耶尔森菌引起的败血症。

Septicaemia due to Yersinia enterocolitica after oral overdoses of iron.

作者信息

Melby K, Slørdahl S, Gutteberg T J, Nordbø S A

出版信息

Br Med J (Clin Res Ed). 1982 Aug 14;285(6340):467-8. doi: 10.1136/bmj.285.6340.467.

DOI:10.1136/bmj.285.6340.467
PMID:6809127
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1499267/
Abstract

Septicaemia occurred after accidental oral overdoses of iron in two previously healthy children. Yersinia enterocolitica serotype 0:3 was recovered from blood and stool cultures in both patients. Enhanced growth of Y enterocolitica in the intestine combined with damage of intestinal mucosa may have been of major importance for the development of generalised infection in these cases. Iron and the iron chelating agent desferrioxamine may possibly have a pathogenetic role in such circumstances.

摘要

两名原本健康的儿童在意外经口过量摄入铁剂后发生了败血症。从两名患者的血液和粪便培养物中均分离出了小肠结肠炎耶尔森菌0:3血清型。在这些病例中，小肠结肠炎耶尔森菌在肠道内的生长增强以及肠黏膜损伤可能对全身性感染的发生起了主要作用。在这种情况下，铁和铁螯合剂去铁胺可能具有致病作用。