饮食中亚油酸摄入量低易引发心肌梗死。
Low dietary intake of linoleic acid predisposes to myocardial infarction.
作者信息
Simpson H C, Barker K, Carter R D, Cassels E, Mann J I
出版信息
Br Med J (Clin Res Ed). 1982 Sep 11;285(6343):683-4. doi: 10.1136/bmj.285.6343.683.
Abstract
Thirty-two men who had recently had a myocardial infarction were matched individually for age with controls who had no evidence of heart disease. The patients had a significantly lower proportion of linoleic acid and a higher proportion of palmitic acid in their plasma triglyceride fatty acids. Analysis of the composition of red-cell membrane phosphatidyl choline, which reflects long-term dietary fat intake, showed a significantly lower proportion of linoleic acid in the patients.These differences suggest that the type of dietary fat consumed might be an important factor in the genesis of ischaemic heart disease.
摘要
32名近期发生心肌梗死的男性患者按年龄与无心脏病证据的对照组进行个体匹配。患者血浆甘油三酯脂肪酸中亚油酸比例显著降低，棕榈酸比例升高。对反映长期膳食脂肪摄入的红细胞膜磷脂酰胆碱组成进行分析，结果显示患者中亚油酸比例显著降低。这些差异表明，所摄入膳食脂肪的类型可能是缺血性心脏病发病的一个重要因素。
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本文引用的文献
1
Effects of dietary fats on human erythrocyte fatty acid patterns.膳食脂肪对人体红细胞脂肪酸模式的影响。
J Clin Invest. 1963 May;42(5):675-85. doi: 10.1172/JCI104759.
2
Diet, serum cholesterol, and death from coronary heart disease. The Western Electric study.饮食、血清胆固醇与冠心病死亡。西方电气公司研究。
N Engl J Med. 1981 Jan 8;304(2):65-70. doi: 10.1056/NEJM198101083040201.
3
Haemostatic function and cardiovascular death: early results of a prospective study.止血功能与心血管死亡：一项前瞻性研究的早期结果
Lancet. 1980 May 17;1(8177):1050-4. doi: 10.1016/s0140-6736(80)91498-1.
4
Relationship between fatty-acid composition of platelets and platelet aggregation in rat and man. Relation to thrombosis.大鼠和人类血小板脂肪酸组成与血小板聚集之间的关系。与血栓形成的关系。
Circ Res. 1970 May;26(5):553-64. doi: 10.1161/01.res.26.5.553.
5
Primary prevention of coronary heart disease by diet.通过饮食对冠心病进行一级预防。
Bull N Y Acad Med. 1968 Aug;44(8):936-49.
6
The influence of dietary fats on platelets in man.
Acta Med Scand. 1971 Jul-Aug;190(1-2):27-34.
7
Platelets, fatty acids and thrombosis.血小板、脂肪酸与血栓形成
Circ Res. 1967 Jan;20(1):11-7. doi: 10.1161/01.res.20.1.11.
8
Platelet lipid modifications induced by fatty acids. Experimental studies and correlations with human neuropathology.脂肪酸诱导的血小板脂质修饰。实验研究及其与人类神经病理学的相关性。
Haemostasis. 1973;2(1):118-40. doi: 10.1159/000214014.
9
Studies on human platelet granules and membranes.关于人类血小板颗粒和膜的研究。
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10
Titrating dietary linoleate to in vivo platelet function in man.在人体中滴定膳食亚油酸以调节体内血小板功能。
Am J Clin Nutr. 1975 Jun;28(6):601-5. doi: 10.1093/ajcn/28.6.601.
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