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75硒标记的克氏锥虫血液型锥鞭毛体:慢性感染血清的调理作用有助于在脾脏和肝脏中杀伤病原体。

75Se-methionine labelled Trypanosoma cruzi blood trypomastigotes: opsonization by chronic infection serum facilitates killing in spleen and liver.

作者信息

Scott M T, Moyes L

出版信息

Clin Exp Immunol. 1982 Jun;48(3):754-7.

Abstract

Blood trypomastigote forms of Trypanosoma cruzi have been labelled with 75Se-methionine. Opsonization by sera from mice chronically infected with T. cruzi promoted their uptake by both liver and spleen. Opsonized parasites within spleens and livers were less infectious when transferred to normal recipients demonstrating in situ parasite killing by these organs.

摘要

克氏锥虫的血液型锥鞭毛体已用75Se-甲硫氨酸进行标记。来自慢性感染克氏锥虫小鼠的血清进行调理作用后,促进了肝脏和脾脏对它们的摄取。当将脾脏和肝脏内经调理的寄生虫转移至正常受体时,其感染性降低,表明这些器官可在原位杀死寄生虫。

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