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75硒标记的克氏锥虫血液型锥鞭毛体：慢性感染血清的调理作用有助于在脾脏和肝脏中杀伤病原体。

75Se-methionine labelled Trypanosoma cruzi blood trypomastigotes: opsonization by chronic infection serum facilitates killing in spleen and liver.

作者信息

Scott M T, Moyes L

出版信息

Clin Exp Immunol. 1982 Jun;48(3):754-7.

PMID:6811174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1536600/
Abstract

Blood trypomastigote forms of Trypanosoma cruzi have been labelled with 75Se-methionine. Opsonization by sera from mice chronically infected with T. cruzi promoted their uptake by both liver and spleen. Opsonized parasites within spleens and livers were less infectious when transferred to normal recipients demonstrating in situ parasite killing by these organs.

摘要

克氏锥虫的血液型锥鞭毛体已用75Se-甲硫氨酸进行标记。来自慢性感染克氏锥虫小鼠的血清进行调理作用后，促进了肝脏和脾脏对它们的摄取。当将脾脏和肝脏内经调理的寄生虫转移至正常受体时，其感染性降低，表明这些器官可在原位杀死寄生虫。

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本文引用的文献

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Cell-mediated cytotoxicity to Trypanosoma cruzi. II. Antibody-dependent killing of bloodstream forms by mouse eosinophils and neutrophils.细胞介导的对克氏锥虫的细胞毒性。II. 小鼠嗜酸性粒细胞和中性粒细胞对血流形式的抗体依赖性杀伤。
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Passive protection of mice against infection with Trypanosoma cruzi with plasma: the use of blood- and vector bug-derived trypomastigote challenge.用血浆对小鼠进行克氏锥虫感染的被动保护：使用源自血液和媒介昆虫的锥鞭毛体进行攻击。
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Protective effects of specific antibodies in Trypanosoma cruzi infections.特异性抗体在克氏锥虫感染中的保护作用。
J Immunol. 1976 Mar;116(3):755-60.
8
Immunological clearance of 75Se-labelled Trypanosoma brucei in mice. I. Aspects of the radiolabelling technique.小鼠体内75硒标记布氏锥虫的免疫清除。I. 放射性标记技术的若干方面。
Immunology. 1979 Mar;36(3):415-20.
9
The in vitro interaction of Trypanosoma cruzi bloodstream forms and mouse peritoneal macrophages.克氏锥虫血流型与小鼠腹腔巨噬细胞的体外相互作用。
Acta Trop. 1978 Sep;35(3):209-19.