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多形核白细胞和单核细胞对铜绿假单胞菌的吞噬作用:囊性纤维化血清的影响。

Phagocytosis of Pseudomonas aeruginosa by polymorphonuclear leukocytes and monocytes: effect of cystic fibrosis serum.

作者信息

Thomassen M J, Demko C A, Wood R E, Sherman J M

出版信息

Infect Immun. 1982 Nov;38(2):802-5. doi: 10.1128/iai.38.2.802-805.1982.

Abstract

It has been shown previously that serum from chronically infected patients with cystic fibrosis inhibits the phagocytosis of Pseudomonas aeruginosa by both normal and cystic fibrosis alveolar macrophages. In the present study, the ability of peripheral monocytes and polymorphonuclear leukocytes from normal volunteers and cystic fibrosis patients to phagocytize P. aeruginosa was shown not to be inhibited in the presence of serum from cystic fibrosis patients.

摘要

先前已表明,来自慢性感染囊性纤维化患者的血清会抑制正常和囊性纤维化肺泡巨噬细胞对铜绿假单胞菌的吞噬作用。在本研究中,结果显示,在囊性纤维化患者血清存在的情况下,正常志愿者和囊性纤维化患者的外周单核细胞和多形核白细胞对铜绿假单胞菌的吞噬能力并未受到抑制。

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Opsonic defect in patients with cystic fibrosis of the pancreas.胰腺囊性纤维化患者的调理素缺陷
Proc Natl Acad Sci U S A. 1971 Aug;68(8):1716-9. doi: 10.1073/pnas.68.8.1716.

本文引用的文献

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Opsonic defect in patients with cystic fibrosis of the pancreas.胰腺囊性纤维化患者的调理素缺陷
Proc Natl Acad Sci U S A. 1971 Aug;68(8):1716-9. doi: 10.1073/pnas.68.8.1716.
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Pseudomonas: the compromised host.
Hosp Pract. 1976 Aug;11(8):91-100. doi: 10.1080/21548331.1976.11706983.
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