Meenhorst P L, Reingold A L, Gorman G W, Feeley J C, van Cronenburg B J, Meyer C L, van Furth R
J Infect Dis. 1983 Jan;147(1):129-32. doi: 10.1093/infdis/147.1.129.
An investigation of an outbreak of nosocomial legionella pneumonia revealed that the potable water of the hospital was contaminated with a distinctive strain of Legionella pneumophila (designated the Le-1 strain), which was by culture and serology linked with human illness. To examine the possible role of this water in this outbreak, eight healthy guinea pigs were exposed to an aerosol of concentrated potable water. Seven animals developed pneumonia due to the Le-1 strain of L. pneumophila. In one of these guinea pigs, the Le-1 strain was also isolated from the blood and spleen. These results provide support to the theory that exposure of humans to aerosols of potable water contaminated with L. pneumophila may cause legionella pneumonia.
一项关于医院内军团菌肺炎暴发的调查显示，该医院的饮用水被一种独特的嗜肺军团菌菌株（命名为Le-1菌株）污染，通过培养和血清学检测发现其与人类疾病有关。为了研究这种水在此次暴发中可能起到的作用，八只健康的豚鼠暴露于浓缩饮用水的气溶胶中。七只动物因嗜肺军团菌Le-1菌株而患上肺炎。在其中一只豚鼠的血液和脾脏中也分离出了Le-1菌株。这些结果为以下理论提供了支持，即人类接触被嗜肺军团菌污染的饮用水气溶胶可能会导致军团菌肺炎。
