Wright J P, Marks I N, Jameson C, Garisch J A, Burns D G, Kottler R E
S Afr Med J. 1983 Feb 12;63(7):223-6.
Previously documented and new patients with ulcerative colitis seen between 1975 and 1980 in the Gastro-intestinal Clinic of Groote Schuur Hospital were studied to establish the local incidence and clinical features of this disease. There were 220 patients and the mean follow-up was 7,7 +/- 0,4 years. Sixty per cent of patients were White, 37% Coloured and 3% Black. The incidence for the Coloured and White population was calculated to be 1,3 and 2,4/100 000 per year during 1970-1974 and 1,6 and 2,1/100 000 per year during 1975-1980, respectively. In Jews the rates were 8,5 and 10,4/100 000 per year for the two periods. Insufficient data are available to calculate an incidence for the Black population. The disease was limited to less than 15 cm above the anus in 14% of patients, to the rectosigmoid colon in 45%, and to the rest of the colon in 40%. Although the severity of symptoms was related to the extent of disease, 22% of patients with extensive colitis had mild symptoms, while 15% with disease limited to the rectum had severe symptoms. The clinical features were similar in the White and Coloured population groups. A total colectomy was performed on 20% of patients with extensive colitis; in 2% the disease was complicated by colonic carcinoma.
对1975年至1980年间在格罗特·舒尔医院胃肠科就诊的既往有记录的溃疡性结肠炎患者以及新患者进行了研究，以确定该病的当地发病率和临床特征。共有220例患者，平均随访时间为7.7±0.4年。60%的患者为白人，37%为有色人种，3%为黑人。计算得出，1970 - 1974年期间有色人种和白人的发病率分别为每年1.3/10万和2.4/10万，1975 - 1980年期间分别为每年1.6/10万和2.1/10万。在犹太人中，这两个时期的发病率分别为每年8.5/10万和10.4/10万。尚无足够数据计算黑人的发病率。14%的患者病变局限于肛门以上不到15厘米处，45%局限于直肠乙状结肠，40%累及结肠其余部位。尽管症状的严重程度与疾病范围有关，但22%的广泛性结肠炎患者症状较轻，而15%病变局限于直肠的患者症状严重。白人和有色人种群体的临床特征相似。20%的广泛性结肠炎患者接受了全结肠切除术；2%的患者并发结肠癌。
