Simon J, Young J L, Gutin B, Blood D K, Case R B
J Appl Physiol Respir Environ Exerc Physiol. 1983 Jan;54(1):13-7. doi: 10.1152/jappl.1983.54.1.13.
Anaerobic thresholds of five male subjects were determined invasively (ATi), from a marked increase in plasma lactate above resting levels (delta La), and noninvasively (ATn), from a nonlinear increase in minute ventilation (VE) during incremental work (IW) leg cycling tests; work rate was increased 30 W every 2 min. Each subject also performed four constant-load work (CLW) tasks just above and just below their ATn and respiratory compensation threshold (RCT), i.e., the point expressed as O2 consumption (VO2) or work rate, at which VE increases disproportionally to CO2 output during IW. In four of the five subjects the ATn preceded the ATi during IW. Yet the ATn delineated the CLW in which marked lactate accumulation did or did not occur. During CLW just above the ATn in these same four subjects, VE/VO2 and fractional expired O2 (FEO2) peaked well before delta La plateaued. These findings suggest that exercise hyperventilation is not necessarily proportional to increases in plasma lactate.
通过侵入性方法（ATi），即根据血浆乳酸水平相对于静息水平的显著升高（ΔLa），以及非侵入性方法（ATn），即根据递增负荷腿部骑行测试期间分钟通气量（VE）的非线性增加，测定了五名男性受试者的无氧阈；工作负荷每2分钟增加30瓦。每位受试者还在其ATn和呼吸补偿阈（RCT），即递增负荷期间以氧气消耗量（VO2）或工作负荷表示的、VE相对于二氧化碳排出量不成比例增加的那个点，上下分别进行了四项恒定负荷工作（CLW）任务。在五名受试者中的四名中，递增负荷期间ATn先于ATi出现。然而，ATn界定了会或不会发生显著乳酸堆积的CLW。在这相同的四名受试者中，在略高于ATn的CLW期间，VE/VO2和呼出氧气分数（FEO2）在ΔLa达到平台期之前就达到了峰值。这些发现表明，运动性过度通气不一定与血浆乳酸的增加成正比。
