Leonard D G, O'Duffy J D, Rogers R S
Mayo Clin Proc. 1978 Aug;53(8):511-8.
Among 77 patients hospitalized with psoriasis, 30 (39%) had psoriatic arthritis. Arthiritis was more frequent (P less than 0.05) in those with extensive psoriasis (grades 3 and 4) than in those with less extensive psoriasis (grade 1 and 2). Temporally, flares in skin and joint disease were not closely related. The Moll-Wright classification of psoriatic arthritis into five clinical groups could be loosely applied to our patients. However, sacroiliitis (present in 33% of the patients) was seen in all five groups and was related to HLA-B27 antigen. Although there was no positive correlation between extent of psoriasis and serum urate level, four patients had gout. Mean serum urate level was higher (P less than 0.05) in females with psoriatic arthritis than in females with psoriasis alone. Antinuclear antibodies were found in 6 of 19 patients with psoriatic arthritis and in none of the 11 patients with psoriasis alone.
在77名因银屑病住院的患者中，30名（39%）患有银屑病关节炎。广泛性银屑病（3级和4级）患者的关节炎发生率高于银屑病程度较轻（1级和2级）的患者（P<0.05）。在时间上，皮肤和关节疾病的发作没有密切关系。Moll-Wright将银屑病关节炎分为五个临床组的分类方法可大致应用于我们的患者。然而，骶髂关节炎（33%的患者存在）在所有五个组中均有发现，且与HLA-B27抗原相关。虽然银屑病的严重程度与血清尿酸水平之间没有正相关，但有4名患者患有痛风。银屑病关节炎女性患者的平均血清尿酸水平高于仅患银屑病的女性患者（P<0.05）。19名银屑病关节炎患者中有6名发现抗核抗体，而11名单纯银屑病患者中均未发现。
