Wong E T, Rude R K, Singer F R, Shaw S T
Am J Clin Pathol. 1983 Mar;79(3):348-52. doi: 10.1093/ajcp/79.3.348.
The prevalence of hypomagnesemia and hypermagnesemia among hospitalized patients was studied by determining magnesium levels in 621 serum samples randomly selected from those submitted to the clinical chemistry laboratory for a biochemical test panel. The reference range for serum magnesium was established in this study as 1.2 to 1.9 mEq/L from measurements of serum magnesium on 341 healthy volunteers. Hypomagnesemia (less than 1.2 mEq/L) was present in 68 patients or 11.0%, and hypermagnesemia (greater than 1.9 mEq/L) occurred in 58 patients or 9.3%. The degree of association between hypomagnesemia and hypocalcemia was assessed by measuring serum magnesium on a separate group of 61 patients with hypocalcemia (corrected calcium less than 8.6 mg/dL). Hypomagnesemia was present in 23.3% of patients hypocalcemic in the absence of renal failure; this proportion was higher significantly than the 11.0% who were hypomagnesemic in the hospitalized patient group (P less than 0.025).
通过测定从临床化学实验室提交进行生化检测组合的621份血清样本中的镁水平，研究了住院患者中低镁血症和高镁血症的患病率。本研究通过对341名健康志愿者的血清镁测量，确定血清镁的参考范围为1.2至1.9 mEq/L。68名患者（11.0%）存在低镁血症（低于1.2 mEq/L），58名患者（9.3%）出现高镁血症（高于1.9 mEq/L）。通过对另一组61名低钙血症患者（校正钙低于8.6 mg/dL）测量血清镁，评估低镁血症与低钙血症之间的关联程度。在无肾衰竭的低钙血症患者中，23.3%存在低镁血症；这一比例显著高于住院患者组中低镁血症患者的11.0%（P小于0.025）。
